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Adapalene
Adapalene
active EU restricted
A third-generation retinoid available OTC (Differin). More stable and less irritating than retinol while being more effective for acne. First-line treatment for comedonal acne.
Benefits
Gold standard for acne (comedonal), less irritating than retinol, photostable
Risks & concerns
Drying, peeling in first weeks. Not for use during pregnancy.
Best for
Oily skin Combination skin Normal skin
Avoid if
Dry skin Sensitive skin
Targets these concerns
Technical details
- INCI name
- Adapalene
- CAS Number
- 106685-40-9
- Category
- active
- Comedogenic rating
- 0/5